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Epithalon (also known as Epitalon or Epithalone) is the synthetic version of the polypeptide Epithalamin which is naturally produced in humans. This pineal peptide preparation is secreted in the epithlamium-epiphyseal region of the brain. Its more prominent tasks are: to regulate metabolism in the epiphysis, increase the sensitivity of hypothalamus to its natural hormonal influences, normalize the function of the anterior pituitary, regulate the levels of gonadotropins and melatonin in the body. Epithalamin increases a person’s resistance to emotional stress and also acts as an antioxidant.

Human life extenssion via Telomerase activation and elongation of Telomeres

Epitalon is one of the very few substances which are able to activate Telomerase (telomere terminal transferase) enzyme in humans. Telomerase renews (elongates) the telomeres, which are responsible for protection of the human DNA from damage and cancer causing errors.

Epitalon used for Anti Aging

Epitalon decreases the age-related changes in immune and neuroendocrine systems, reduces the incidence of recurrent infections and chronic diseases. Long term clinical trials have shown that in patients with age-related pathology Epithalamin eliminates imbalance in prooxidation and antioxidation systems.
Results of 12-months treatment with Epithalon in patients with signs of accelerated aging showed normalizing effect on metabolism and condition of various functional systems. Elevated uric acid, alkaline phosphatase and cholesterol in elder patients returned to normal after 10 days of treatment, and remained stable in a several months peroid afterwards.

Epitalon effects

Experimental and clinical studies of Epitalon showed the following pharmaclogical properties of Epithalamin (Epitalon):

• Telomerase activation (consequently, elongation
of Telomeres)
• Regulates neuroendocrinous system
• Increases the hypothalamic sensitivity to the
endogenous hormonal effects
• Decrease or suppression of proliferative changes
in vaginal epithelium and endometrium in
anovulatory phase
• Normalization of gonadotropic hormones levels
(FSG, LG, prolactin)
• Positive influence on peripheral haemodynamics:
improvement of blood rheology, decrease of
intravessel thrombogenesis
• Regulation of the levels of reactants in the acute
inflammation phase (c3-component of the
complement, pre-albumin, C-reactive protein,
• Normalization of T-cell immunity
• Normalization of aqua-electrolyte balance indices
• Normalization of uric acid levels
• Normalization of Cholesterol
• Rejuvenation / strengthening of the immune
• Inhibition of spontaneous and induced
carcinogenesis (tumor prevention)

Epitalon side effects

There have been no reported side effects of Epithalon in any of the clinical and experimental trials. Likewise there are no reports of any Epithalamin adverse reactions on various internet forums, where people have been documenting repeated courses every 10-15 days for several years.

Epithalon dosage and course (cycle) duration

Dosage depends on the purpose and severity of the damage which is treated. Epitalon can be used orally (less effective and large dose) or injected intramuscularly or under the skin (more effective at much smaller dose).

Injectable Epithalon use:

• Duration: 10 – 20 days
• Dosage: between 5 – 10 mg per day (20 mg
intravenous for terminal patients)
• Frequency of injection:1 injection per day for low
dose, 2 injections for higher dose (divided
between morning and late afternoon injection)

Each 10 – 20 days course of Epithalamin is followed by 4-6 months pause before repeating the course again. Epitalon treatment can be repeated indefinitely.


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